Dr. Dubekile Nyoni

Dr. Dubekile Nyoni

Lecturer - Applied Chemistry

Qualifications

PhD, Physical Organic Chemistry , Rhodes University, South Africa 2011. Title of Thesis”Mechanistic Studies of Unusual Morita-Baylis-Hillman Reactions”

MSc, Organic Chemistry Rhodes University, South Africa - 2007. Title of Thesis “Application of the Baylis-Hillman methodology in the construction of novel heterocyclic derivatives”

BSc (Honours), Chemistry Midlands State University, Zimbabwe 2004

 

Publications by Dr. Dubekile Nyoni

1. ‘Baylis-Hillman-derived N,N’-Disubstituted Piperizines: Structural and Preliminary Computational Studies’; Idahosa, K. C.; Lee, Y-C.; Nyoni, D.; Kaye, P. T.; Caira, M. R., Tetrahedron Lett., 2011, 52(23), 2972-2976.

2. ‘DBU-mediated Cleavage of Aryl and Heteroaryl Disulphides’; Nyoni, D.; Lobb, K. A.; Kaye, P. T.; Caira, M. R., ARKIVOC, 2012, (vi), 245-252.

3. ‘Dual-catalyst acceleration of tandem disulphide cleavage- Baylis-Hillman synthesis of 2H-1-benzothiopyran derivatives’; Nyoni, D.; Lobb, K. A.; Kaye, P. T., Synth. Commun., 2013, 43:13, 1837-1841.

4. ‘Heterometallic half-sandwich complexes containing a ferrocenylhydrazone motif: Synthesis, molecular structure, electrochemistry and antiplasmodial evaluation’; Nkoana, W.; Nyoni, D.; Chellan, P.; Stringer, T.; Taylor, D.; Smith, P. J.; Hutton, A. T.; Smith, G. S., J. Organomet. Chem., 2014, 752, 67-75.

5. ‘Kinetic and theoretical studies of the 1,8-diazabicyclo[5.4.0]-undec-7-ene (DBU)-mediated formation of 2H-1-benzothiopyran derivatives under Baylis-Hillman conditions’; Nyoni, D.; Lobb, K. A.; Kaye, P. T., manuscript is in preparation.

6. ‘Resolving Morita-Baylis-Hillman enantiomers: A Biocatalysis Approach’; Nyoni, D.; Bode, M. L.; Brady, D., manuscript in preparation.

7. ‘Synthesis of aromatic amides using purified nitrile hydratase’; Dubekile Nyoni, Peter J. Wanyama, Varsha Chhiba, Naadiya Patel, Tshepiso Mpala, Moira L. Bode and Dean Brady, manuscript in preparation

 

Conferences

1. Ganto, M. M.; Nyoni, D.; Klein, R.; Kaye, P. T., poster presentation, SACI Conference, Durban, December 2006.

2. Brown, M. E.; Duggan, A. R.; Ganto, M. M.; Kaye, P. T.; Klein, R.; Lobb, K. A.; Mciteka, L.; Molefe, D. M.; Nyoni, D. ‘Synthetic and mechanistic studies of Baylis-Hillman-type reactions’, poster presentation at BOCC’08, Bi-national Organic conference, Kruger National Park, September 2008.

3. Nyoni, D.; Lobb, K. A.; Kaye, P. T., poster presentation, BOCC conference, Petermaritzburg, January 2010

4. Nyoni, D.; Lobb, K. A.; Kaye, P. T., oral presentation, Interdisciplinary Post Graduate Conference, Rhodes University, September 2011.

5. Nyoni, D.; Lobb, K. A.; Kaye, P. T., poster presentation, ASSAF-DST-NRF Young Scientist’s Conference, Pretoria, Sept 2011.

6. Nyoni, D.; Mokone, W.; Wanyama P. J.; Bode, M. L.; Brady, D.,poster presentation, CATSA conference, 12-14 November 2014, St Georges Hotel and Conference Center, Pretoria

7. Nyoni, D.; Wanyama P. J.; Bode, M. L.; Brady, D.,poster presentation, BOCC conference, 28 November- 4 Dec 2014, Stellenbosch University